As Nate noted some months ago, the Medical Device Tax has put a crimp in the medical R&D sector. The latest casualties of this component of the ObamaTax are the 1,000 soon-to-be-former employees of Michigan-based Stryker.

Adding insult to injury, the beleagured firm also owes Uncle Sugar some $100 million just from this year, and it's estimated to "cost the company fully 20 percent of its total research and development investments."

Train. Wreck.